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Republican-led health care reform is facing an uncertain future in the Senate.

FOX's Rachel Sutherland reports from Washington:

As the Senate gets ready to take up health care, President Obama is calling on lawmakers to think twice before rolling back his signature accomplishment:

(Obama) "It does require some courage to champion the vulnerable, and the sick and the infirm."

The former President spoke while accepting the JFK Profile in Courage Award in Boston. Republican Senator Susan Collins says the upper chamber will start from scratch:

(Collins) "We're going to draft our own bill."

There's no timetable yet on a Senate-crafted health care bill.

In Washington, Rachel Sutherland, FOX News.

Follow Rachel Sutherland on Twitter: @SutherlandFOX